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Excipients

InhaLac® from MEGGLE – sieved, milled, micronized and tailor-made.
High quality crystalline lactose, designed for dry powder inhaler.

InhaLac® stands for a lactose, which is, in particular, suitable for use in pulmonary and nasal drug delivery.

Inhalation aerosols offers the potential for needle-free systemic delivery of small molecule drugs as well as therapeutic peptides and proteins. An industry standard in dry powder inhalation formulation development, lactose monohydrate is used safely in DPI formulations. Using lactose as an excipient not only improves performance efficiency of the inhaler, but also facilitates powder handling during production. Effective performance of a dry powder inhaler largely depends on the carrier material used for the drug formulation.

With our highly controlled production process different high quality grades for inhalation are obtained, providing an adequate range of particle sizes - making them behaves as individual particles.

Benefits of InhaLac®:
  • Highly controlled powder characteristics
  • Highest microbial quality including endotoxins
  • A broad spectrum of sieve cuts
  • Tailor-made sieved, milled and micronized grades
  • Customized product specifications

InhaLac® - sieved

InhaLac® 70

  • Particle size distribution
  • x10 110-160 µm
  • x50 180-250 µm
  • x90 270-340 µm
  • Typical Values
  • Bulk Density 0.6 g/ml
  • Tapped Density 0.71 g/ml

InhaLac® 120

  • Particle size distribution
  • x10 70-105 µm
  • x50 110-155 µm
  • x90 160-215 µm
  • Typical Values
  • Bulk Density 0.72 g/ml
  • Tapped Density 0.83 g/ml

InhaLac® 160

  • Particle size distribution
  • x10 55-85 µm
  • x50 90-120 µm
  • x90 125-165 µm
  • Typical Values
  • Bulk Density 0.7 g/ml
  • Tapped Density 0.835 g/ml

InhaLac® 230

  • Particle size distribution
  • x10 30-60 µm
  • x50 70-110 µm
  • x90 110-150 µm
  • Typical Values
  • Bulk Density 0.7 g/ml
  • Tapped Density 0.85 g/ml

InhaLac® 251

  • Particle size distribution
  • x10 7-22 µm
  • x50 40-70 µm
  • x90 80-120 µm
  • Typical Values
  • Bulk Density 0.64 g/ml
  • Tapped Density 0.88 g/ml

InhaLac® - milled

InhaLac® 140

  • Particle size distribution
  • x10 3 - 7 µm
  • x50 37 - 61 µm
  • x90 120 - 190 µm
  • Typical Values
  • Bulk Density 0.6 g/ml
  • Tapped Density 0.92 g/ml

InhaLac® 150

  • Particle size distribution
  • x10 1 - 5 µm
  • x50 18 - 30 µm
  • x90 65 - 95 µm
  • Typical Values
  • Bulk Density 0.49 g/ml
  • Tapped Density 0.8 g/ml

InhaLac® 400

  • Particle size distribution
  • x10 0.8-1.6 µm
  • x50 4.0-11.0 µm
  • x90 15.0-35.0 µm
  • Typical Values
  • Bulk Density 0.33 g/ml
  • Tapped Density 0.53 g/ml
micronized

InhaLac® 500

  • Particle size distribution
  • x10 -
  • x50 NMT 5 µm
  • x90 NMT 10 µm
  • Typical Values
  • Bulk Density 0.24 g/ml
  • Tapped Density 0.37 g/ml
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